Search results for "Androgen Metabolism"

showing 2 items of 2 documents

Sex hormones modulate inflammatory mediators produced by macrophages.

1999

Lipopolysaccharidesmedicine.medical_specialtyNitric oxide biosynthesisReceptors EstradiolNitric OxideGeneral Biochemistry Genetics and Molecular BiologyCell LineHistory and Philosophy of ScienceInternal medicinemedicineAnimalsTestosteroneReceptorEstradiolbusiness.industryTumor Necrosis Factor-alphaGeneral NeuroscienceMacrophagesTumor Necrosis Factor alpha biosynthesisAndrogen MetabolismInterleukin-10EndocrinologyCell cultureReceptors AndrogenInflammation MediatorsbusinessHormoneAnnals of the New York Academy of Sciences
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Androgen metabolism in the skin of the rainbow trout (Oncorhynchus mykiss)

1993

Pieces of skin of male and female rainbow trout (Oncorhynchus mykiss) were incubated with testosterone and 11-ketotestosterone as substrates. In immature fish the conversion rate was low. In non-spawning adult males 11-ketotestosterone was reduced to 5α-11KDHT (up to 5.2%). In the fish in spawning condition the 5α-reduction rate was only about 1 to 2%. In the same specimens incubated with testosterone a high 11β-hydroxylase activity (23.8-25% in the male and 13% in the female skin) was found. Similar sex specific differences were observed for the occurence of 5α-reduced metabolites (about 20% in the male and 13% in the female tissue).

medicine.medical_specialtyurogenital systemPhysiologyGeneral MedicineAquatic ScienceBiologyBiochemistrySex specificAndrogen Metabolism5α reductaseFisheryEndocrinologyInternal medicinemedicineFish <Actinopterygii>Rainbow troutTestosteroneFish Physiology and Biochemistry
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